• Genome-wide Phenotypic Profiling Identifies and Categorizes Genes Required for Mycobacterial Low Iron Fitness 

      Dragset, Marte Singsås; Ioerger, Thomas R.; Zhang, Yanjia; Mærk, Mali; Ginbot, Zekarias; Flo, Trude Helen; Rubin, Eric J; Steigedal, Magnus (Journal article; Peer reviewed, 2019)
      Iron is vital for nearly all living organisms, but during infection, not readily available to pathogens. Infectious bacteria therefore depend on specialized mechanisms to survive when iron is limited. These mechanisms make ...
    • Patient derived colonoids as drug testing platforms-Critical importance of oxygen concentration 

      Skovdahl, Helene Kolstad; Gopalakrishnan, Shreya; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Bakke, Ingunn; Ginbot, Zekarias; Thorsvik, Silje; Flatberg, Arnar; Sporsheim, Bjørnar; Ostrop, Jenny; Mollnes, Tom Eirik; Sandvik, Arne Kristian; Bruland, Torunn (Peer reviewed; Journal article, 2021)
      Treatment of inflammatory bowel disease (IBD) is challenging, with a series of available drugs each helping only a fraction of patients. Patients may face time-consuming drug trials while the disease is active, thus there ...